Viscous Injectables
Hyaluronic Acid Gels
Injectables for Controlled Slow Drug Release
Contained Homogenising
Kriegers Contained Mixing and Homogenising processing Technology provides the most user friendly system on the market to operate, control and validate sterile and contained manufacturing processes.
The technological breakthrough in elimination cooling liquid and seal and scraper debris in Kriegers contained systems, makes our contained technology the forerunner for products like:
- Viscoelastics,
- Viscous injectables,
- Hyaluronan based Gels
- Complex Contained/Sterile products
Contained MMU 25 at the washing station
10 X Faster process times then traditional equipment
Hyaluronic Acid Powder or Hyaluronan Fibers are quickly dissolved and active ingredients (API’s) are perfectly homogenized into the final gel thanks to our special designed agitating tools for mixing and homogenizing Hyaluronan and sterile viscous compounds.
Absolute Containment: The Krieger Seal Containment Chamber
The Krieger Seal Containment Chamber (SCC) ensures an absolute particle free and contained mixing zone. The SCC eliminates cooling liquids and seal and scraper debris in Sterile and Contained counter rotating mixing Systems.
No Scraper Debris thanks to near to the wall scraper agitator
The near to the wall agitator arm ensures a contained environment for perfect heat transfer and an optimal homogenisation process without the use of traditional wall scrapers.
100% homogeneous API Distribution
Our high performance counter rotating agitating tools are foreseen with an „in valve mixing device“.
The in valve mixing ensures 100% homogeneous API distribution in the entire batch even in the difficult to mix zone around the bottom outlet valve. This allows direct transfer from the batch to a filling line for small vials.
Seamless Low to High Viscosity Processing
Viscous injectables with API's for controlled drug release: Thanks to our in valve mixing tool a 500 liter batch can transfer directly to a vials filling line. Viscosity from 5000 cps up to 200’000 cps.
Easy Cleaning / Easy Sterilisation Procedures
The self draining vessel has built in spray pipes to clean the vessel surfaces
Sterilisation procedures are easy as the SCC works without cooling liquids for the Mechanical seals , No validation and expensive hardware are required to obtain a sterile cooling liquid.
On board temperature verification system with steam drain traps for easy sterilization.
Haluronic Acid processing at Lifecore Biomedical
MMU 25 Contained for Viscoelastics
MMD 1000 Contained at Baxter Bioscience
