Products
Swiss-Engineered Processing Equipment.
From laboratory development to production-scale manufacturing, Krieger develops advanced mixing, homogenization and processing equipment for demanding pharmaceutical, biotech and cosmetic applications.
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K-Mix
The K-Mix is an advanced mixing and homogenizing system designed for the processing of low- to high-viscosity semi-solids under aseptic conditions. Its flexible modular design allows the system to be configured according to specific process requirements, with scalable solutions for pharmaceutical, cosmetic, healthcare and toiletry applications.
Ideal for: Pharmaceutical formulations · Cosmetics · Healthcare · Toiletries · Semi-solids · Low- to high-viscosity products
Key Features
Aseptic design with cGMP-compliant housing
Counter-rotating mixing tools and integrated C-TH homogenizer
Validated CIP/SIP system for hygienic processing
Flexible modular design with integrated utility rack and configurable building blocks
Applications
The K-Mix is designed for the manufacturing and processing of low- to high-viscosity semi-solid products under aseptic conditions. It is suitable for a wide range of pharmaceutical, cosmetic, healthcare and toiletry applications, providing controlled mixing and homogenization with flexible process configurations.
Technical Information
Aseptic processing · cGMP housing · Counter-rotating mixing tools · C-TH homogenizer · Integrated CIP/SIP · Powder injection system · Validated gear box · GAMP user interface · Touchscreen operator panel · Balanced shear · Operating range: -0.1 to 2 bar · Configurable modular design
Molto-Mat Contained
The Molto-Mat Contained is a high-containment sterile processing system designed for shear-sensitive biologics, viscous injectables and plasma preparations. Its contained design combines low-shear homogenization, vacuum processing and direct-to-filling capabilities for demanding pharmaceutical applications.
Ideal for:
Pharmaceutical formulations · Biologics · Viscous injectables · Plasma preparations · Shear-sensitive products
Key Features
High-containment sterile design for demanding pharmaceutical processes
Low-shear homogenization with counter-rotating mixing tools
Direct-to-filling processing with a sealed mixing chamber
Scalable from 5 L to 1000 L for development through production
Applications
The Molto-Mat Contained is designed for the sterile processing of shear-sensitive biologics, viscous injectable formulations and plasma-based products. Its contained configuration helps minimize particulate contamination while providing controlled mixing, homogenization and vacuum processing in accordance with GMP requirements.
Technical Information
cGMP design · Counter-rotating mixing tools · Low-shear homogenization · Sealed mixing chamber · Direct-to-filling · Integrated CIP/SIP · Vacuum processing up to 3 bar · Powder injection system · Heat transfer without wall scrapers · Combined utility rack · GAMP-compliant software · Quick clamp opening/closing · Scalable from 5 L to 1000 L · FDA / PED / cGMP
Lab Mi-Molto
The Mi-Molto is a compact laboratory mixing system designed for formulation development and R&D applications. It enables the processing of small product quantities and the optimization of formulations before seamless scale-up to industrial Krieger production systems.
Ideal for:
Laboratory & R&D · Formulation Development · Pharmaceutical Formulations · Cosmetics · Gels · Small-Batch Processing
Key Features
Precise laboratory mixing for formulation development
Process parameter simulation to optimize production processes
Recipe and data management for controlled and reproducible development
Seamless scale-up from laboratory batches to industrial Krieger systems
Applications
The Mi-Molto is designed for laboratory and R&D departments developing new formulations, allowing small quantities to be tested and optimized under controlled process conditions. Its flexible design supports the development of creams, gels, ointments and emulsions, while providing a reliable basis for subsequent scale-up to production equipment.
Technical Information
Typical working volume: approx. 1.5–3 L · Glass vessel · Temperature control via heating/cooling jacket · Easy-to-use operator panel · Compact footprint · Recipe and data management · Process parameter simulation · Ideal for laboratory environments · Designed for easy scale-up to industrial Krieger systems
HA Mi-Molto
The Mi-Molto HA is a modular vacuum mixing system designed for the formulation and process development of hyaluronic acid (HA) hydrogels and cross-linked HA gels, from low to high viscosities. Its counter-rotating mixing tools provide efficient processing while enabling seamless scale-up from development to pilot and production systems.
Ideal for:
Pharmaceutical formulations · Hyaluronic Acid Hydrogels · Cross-linked HA Gels · Cosmetics · High-viscosity products
Key Features
Counter-rotating mixing tools specifically designed for HA processing
Vacuum processing for efficient and controlled formulation
Fast HA dissolving, cross-linking, caking, gel cutting and crushing
GMP-compliant design with IQ/OQ documentation available
Applications
The Mi-Molto HA is designed for formulation development and processing of hyaluronic acid hydrogels and cross-linked HA gels. Depending on product viscosity and characteristics, it enables efficient dissolving, cross-linking, caking, cutting and crushing. Products developed on the Mi-Molto HA can be seamlessly transferred to Krieger pilot plants and production-scale machines.
Technical Information
Modular vacuum mixing system · Counter-rotating HA agitator · GMP-compliant design · Low- to high-viscosity processing · IQ/OQ documentation available · Scale-up to pilot and production equipment
MMU Contained
The MMU Contained is Krieger's advanced contained mixing and homogenizing platform, engineered for sterile manufacturing of high-value and high-viscosity pharmaceutical products. Its innovative containment technology eliminates cooling liquid contamination, seal leakage and scraper debris, delivering safer processing, faster production cycles and simplified validation for GMP manufacturing.
Ideal for:
Viscoelastics · Viscous Injectables · Hyaluronan-Based Gels · Sterile Products · Contained Manufacturing · High-Viscosity Formulations
Key Features
Absolute product containment with Krieger's Seal Containment Chamber
Up to 10× faster processing than conventional equipment
100% homogeneous API distribution throughout the batch
Seamless processing from low- to high-viscosity formulations
Applications
The MMU Contained is designed for sterile and contained manufacturing of complex pharmaceutical formulations where product integrity and operator safety are critical. Its advanced processing technology supports the production of viscoelastics, viscous injectables, hyaluronan-based gels and other high-value contained products, while minimizing contamination risks and ensuring consistent process performance.
Technical Information
Contained mixing and homogenizing system · Krieger Seal Containment Chamber · Absolute containment · Up to 10× faster processing · No cooling liquid contamination · No seal or scraper debris · 100% homogeneous API distribution · Low- to high-viscosity processing · Easy cleaning and sterilization · GMP-compliant processing
Micro Mixer
The Krieger Micro Mixer is a compact research and development system designed for small-scale mixing of sensitive pharmaceutical and biologic products under controlled pressure or vacuum conditions. It enables researchers to reproduce manufacturing mixing patterns at laboratory scale, providing a reliable platform for drug development and process scale-up.
Ideal for:
Biologics · Small Molecule Drug Candidates · Shear-Sensitive APIs · Proteins · Pharmaceutical R&D · Contained Processing
Key Features
Small-scale processing from 25 ml, ideal for expensive or limited-volume products
Vacuum or pressure processing with controlled mixing conditions
Scalable mixing geometry designed to mimic manufacturing equipment
Autoclavable and portable vessel for contained filling, emptying and handling
Applications
The Micro Mixer is designed for pharmaceutical and biopharmaceutical R&D, particularly for the development and processing of small-molecule and complex biologic drug candidates, proteins and shear-sensitive active ingredients. Its controlled mixing environment allows researchers to reproduce manufacturing conditions on a significantly smaller scale while supporting a reliable transition toward larger processing equipment.
Technical Information
Minimum processing volume: 25 ml · Available vessel sizes from 0.1 to 10 L · Vacuum and pressure processing · Controlled mixing speed · Temperature control · Autoclavable vessel · Portable/detachable vessel · Top- or bottom-driven mixing configurations · Scaled-down mixing geometry · Suitable for contained processing and biologics R&D
HA Processing Systems
Krieger Systems provide a complete solution for hyaluronic acid (HA) processing, covering the entire process from laboratory formulation development to full-scale production. Designed for the controlled processing of sensitive and highly viscous polymers, Krieger technology enables reliable scale-up, consistent product quality and reproducible manufacturing.
Ideal for:
HA Hydrogels · Cross-linked HA Gels · Pharmaceutical Formulations · Cosmetic Applications · High-viscosity Products
Key Features
Seamless scale-up from Mi-Molto development systems to Molto-Mat and K-Mix production equipment
Controlled mixing technology optimized for shear-sensitive HA structures
Efficient powder incorporation for reliable and controlled HA hydration
Vacuum processing capability to improve wetting and minimize air inclusion
Applications
Krieger HA processing systems are designed for formulation development, hydration, mixing and production of hyaluronic acid-based products. The complete processing platform supports a smooth transition from laboratory development to industrial manufacturing while maintaining consistent process parameters and product quality.
Technical Information
Laboratory-to-production scale-up · HA hydration and viscosity development · Counter-rotating mixing technology · Powder incorporation · Vacuum processing · Shear-sensitive polymer processing · Reproducible batch processing · Mi-Molto · Molto-Mat · K-Mix · Pharmaceutical and cosmetic applications
Advanced Applications
The Quality by Design (QbD) approach provides tailored technology for complex and challenging semi-solid processing applications. Krieger develops dedicated solutions for complex or novel formulations that cannot be efficiently handled by standard processing systems, combining process development, laboratory studies, prototyping and advanced simulation.
Ideal for:
Complex formulations · Sterile processing · High-viscosity products · High-risk formulations · Novel semi-solids · Pharmaceutical & cosmetic applications
Key Features
Custom-engineered systems based on QbD principles
Laboratory studies, prototyping and 3D process simulation
Empirical and theoretical process design
Process validation supporting regulatory requirements
Applications
Krieger's Quality by Design methodology is designed for specialized and demanding semi-solid processing applications where conventional solutions are not sufficient. Each system is developed around the specific product and process requirements, enabling optimized equipment design, process validation and reliable production of sterile, high-viscosity and complex formulations.
Technical Information
Quality by Design methodology · Custom-engineered processing systems · Laboratory process studies · Prototyping · 3D simulation · Empirical & theoretical process design · Process validation · Sterile processing · High-viscosity applications · Complex and novel formulations · Pharmaceutical & cosmetic applications
K.GELPART™ Lab
The K.GELPART™ Lab is a compact hydraulic sieve press system designed for the controlled reduction of particle size in highly viscous gels and pastes. A hydraulic cylinder drives a plunger vertically through the vessel, forcing the product through precision sieves positioned at the bottom. The processed material is then collected in a separate container, providing a simple and efficient solution for laboratory-scale gel processing.
Ideal for:
Highly Viscous Gels · Viscous Pastes · Pharmaceutical Formulations · Cosmetic Gels · Laboratory & R&D · Particle Size Reduction
Key Features
Hydraulic pressing system with vertically driven plunger
Precision sieve processing for controlled particle size reduction
Efficient handling of highly viscous materials
Separate collection vessel for easy product recovery and handling
Applications
The K.GELPART™ Lab is designed for laboratory and formulation development applications where highly viscous materials require particle size reduction and improved product uniformity. The system is particularly suitable for pharmaceutical and cosmetic gels, enabling controlled sieve processing before further formulation or production steps.
Technical Information
Processing volume: 1–3 L · Hydraulic cylinder and plunger system · Precision sieve system · Vertical pressing movement · Separate product collection vessel · High-viscosity processing · Laboratory and R&D applications
K.GELPART™ Pro (10-15L)
The K.GELPAART™ Pro is a hydraulic sieve press system designed to reduce the particle size of highly viscous pastes and gels. By applying controlled hydraulic pressure, the product is forced through a precision sieve, producing a finer and more uniform particle structure while maintaining efficient processing of high-viscosity materials.
Key Features
Hydraulic pressing technology for efficient processing of highly viscous products
Controlled particle size reduction through a precision sieve system
Designed for high-viscosity gels and pastes that are difficult to process with conventional equipment
Consistent and homogeneous product structure after sieve processing
Ideal for: Highly Viscous Gels · Viscous Pastes · Hyaluronan-Based Gels · Pharmaceutical Formulations · Cosmetic Gels · Particle Size Reduction
Applications
The K.GELPART™ Pro is particularly suited for pharmaceutical and cosmetic applications where particle size, texture and product homogeneity are critical. The system enables highly viscous gels and pastes to be efficiently pressed through a sieve, supporting controlled particle size reduction and improved final product consistency.
Technical Information
Processing volume: 10–15 L · Hydraulic sieve press system · High-viscosity processing · Controlled pressure application · Precision sieve system · Particle size reduction · Suitable for gels and viscous pastes · Designed for pharmaceutical and cosmetic processing